Efficacy of Mouthwash Containing Curcuma xanthorrhiza on Lactoperoxidase System Activity and Halitosis Risk
Stella Lesmana, Risqa Rina Darwita, Anton Rahardjo,
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( Stella Lesmana ) - University of Indonesia Faculty of Dentistry Department of Dental Public Health and Preventive Dentistry
( Risqa Rina Darwita ) - University of Indonesia Faculty of Dentistry Department of Dental Public Health and Preventive Dentistry
( Anton Rahardjo ) - University of Indonesia Faculty of Dentistry Department of Dental Public Health and Preventive Dentistry
KMID : 1157520130090040207
Abstract
Objective: The use of mouthwash may increase the activity of lactoperoxidase system in saliva and may reduce the risk of halitosis. The research was conducted to determine the effect of mouthwash containing Curcuma xanthorrhiza on lactoper-oxidase system activity in relation to halitosis risk.
Methods: The research design was a before after clinical trial, the 5 ml saliva samples were taken from 10 subjects age 20-23 years oldat 22.00 WIB at night and at 04.00 WIB in the morning. Lactoperoxidase enzyme activity was measured using the method of Chance and Maehly while the concentration of thiocyanate ion was measured using Thomas and Aune method.
Results: The mean±SD of the baseline lactoperoxidase activity absorbance in the evening 0.2463333±0.126053 and then decreased in the morning to 0.1994999±0.059258 and the mean±SD baseline thiocyanate ion from 1.9328±0.187181 in the night decreased in the morning to 1.819±0.510573. After intervention with mouthwash containing Curcuma xanthor-rhiza, theincreasing of average value of baseline Lactoperoxidase activity absorbances was indicated from 0.2121±0.107991 in the evening becomes 0.240233±0.091862 in the morning, while the average of thiocyanate ion from 1.0531±0.108838 in the evening becomes 1.090267±0.285835 in the morning. There were no significant differences between the activity of lactoperoxidaseenzyme and thiocyanate ion concentrations in both treatments (p＞0.05).
Conclusion: The use of mouthwash containing Curcuma xanthorrhiza has the potential to raise the lactoperoxidase system activity.
키워드
saliva; lactoperoxidase; thiocyanate; halitosis; mouthwash
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